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Antimicrobial Activity and HPLC Profiling of Aqueous Bark of Mango

ANTIMICROBIAL ACTIVITY AND HPLC PROFILING OF AQUEOUS BARK OF MANGO


ABSTRACT

The study investigates the Antimicrobial Activity and HPLC Profiling of Aqueous Bark of Mango. In achieving this aim, the following specific objectives were laid out as follows to: identify the HPLC Profiling of Aqueous Bark of mango, analyze the Hexane-ethyl Acetate Extract of mango and examine the antimicrobial activity of leaf extract of Mangifera Indica. The leaf of mangifera indica; studies with the aim of determined the following photochemical parameters for these species microscopial characters. Leaf contents, photochemical content, about 6 extract (methanol, acetone, hexane, ethyl acetate, hexane-ethyl acetate, aqueous extraction) from the leaves of Mangifera indica was extracted. Hexane-ethyl acetate was characterized by Gas Chromatography- Mass Spectroscopy. The antimicrobial activity of different extract was tested against human and plant pathogenic bacteria. Hexane-ethyl acetate extract showed significant role on inhibiting almost all tested pathogenic organisms. This study will be of immense benefit to researchers who intend to know more on this study and can also be used by non-researchers to build more on their research work. This study contributes to knowledge and could serve as a guide for other study.


CHAPTER ONE

1.1 Introduction

Mango has anti malaria effect (Tsabang et al., 2011) and was found to display in vitro activity against Plasmodium falciparum (Rasoanaivo et al., 2004). Methanol extract of M. indica seeds was done against 61 bacterial strains. The extract showed potent antibacterial activity against all strains tested (Vaghasiya et al., 2011). The leaves of M. indica have been reported to possess antibacterial activity against E. coli and other bacteria in the family Enterobacteriaceae and the bioactive component mangiferin which was isolated from M. indica was reported to possess remarkable anti-influenza activity (Doughari et al., 2008).

As a prelude to other parts of this study, this chapter will discuss the background upon which this study was initiated, the statement of problems that led to this study, the Aim and Objectives of the study. Others are Significance of the study, Scope of work, Research hypothesis and questions, Limitations of the Study and Definition of technical terms.


CHAPTER TWO

2.0 Literature Review

2.1 Introduction

The review of relevant literature is the main topic of this chapter. A literature review covers theoretical and methodological contributions to a certain issue in addition to the state of knowledge at the time of writing. It provides information about the state of the art in relation to the subject you are writing about. It examines the body of work on the chosen subject. The literature evaluation in this study comprises the …


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TABLE OF CONTENTS

PRELIMINARY PAGES


CHAPTER ONE

INTRODUCTION


    • 1.1 Introduction
    • 1.2 Background …

    CHAPTER TWO

    LITERATURE REVIEW

    • 2.1 Introduction

    CHAPTER THREE

    MATERIALS AND METHODS

    • 3.1 Introduction

    CHAPTER FOUR

    RESULTS AND DISCUSSION

    • 4.1 Introduction
    • 4.2 Results
    • 4.3 Discussion of Findings

    CHAPTER FIVE

    SUMMARY, CONCLUSION AND RECOMMENDATION

    • 5.1 Introduction
    • 5.2 Summary
    • 5.3 Conclusion
    • 5.4 Recommendation

    REFERENCES


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